Dr Hon Wei Min Email: [email protected] 教授韩慧敏博士于2013年4月开始担任马来西亚伍伦贡伯乐学府的副校长(学术),负责监督及加强学府、学术课程和教学大纲的策略性发展。 由韩慧敏博士领导的各项发展领域旨在改善和加强学术授课过程。 此外,她还负责制定和改进学术方案,包括设计和审查学术课程。 在加入教育行业之前,她在新加坡一家快速发展的区域生物技术公司担任副总裁,负责领导公司的生命科学业务。 在考取博士学位后,她很快地投身于研究工作,因而积累了多年丰富的研究经验。她还发表了许多关于生物技术和分子生物学的期刊。 直到今日,韩慧敏博士仍不断埋头从事她的研究工作,并积极参与多项研究项目。她对这一领域的热情体现在她不断培养学生的研究兴趣,帮助许多本科生和研究生取得优异的学术证书。 韩慧敏博士毕业于新加坡国立大学,获得理学学士学位和理学学士(荣誉)学位。1997年她在同一所大学也获得了博士学位。她是新加坡生物化学和分子生物学学会(Singapore Society for Biochemistry and Molecular Biology)的理事会成员,也是马来西亚生物化学和分子生物学学会(Malaysian Society for Biochemistry and Molecular Biology)的成员。 资格 博士 (新加坡国立大学,1993-1997年) 研究项目:腺苷对内毒素血症期间一氧化氮合酶表达的影响。 理学学士 (生物化学,二等上荣誉学位,新加坡国立大学1992-1993年) 研究项目: Stonustoxin对血小板聚集的影响。 理学学士 (新加坡国立大学1989-1992年) 研究与出版 Year Title 2017 CS Soo, WS Yap, WM Hon, N Ramli, MS Umi Kalsom, LY Phang. Improvement of hydrogen yield of ethanol-producing Escherichia coli recombinants in acidic conditions. Electronic Journal of Biotechnology 26: 27–32 (2017). Impact factor: 1.527 CS Soo, WS Yap, WM Hon, N Ramli, MS Umi Kalsom, LY Phang. Co-production of Hydrogen and Ethanol of Escherichia coli SS1 Isolate. Chiang Mai J. Sci. 44(3) : 768-773 (2017). Impact factor: 0.409 CS Soo, WS Yap, WM Hon, N Ramli, MS Umi Kalsom, LY Phang. Co-production of hydrogen and ethanol by Escherichia coli SS1 and its recombinant Electronic Journal of Biotechnology 30: 64-70 (2017). Impact factor: 1.527 Journal Publications (Indexed Journal) PCL Koh, Z Rahman, WM Hon, SB Baboo. Design for Visibility and Wellness: Looking into Design Elements on Nutritional Labels. The International Journal of Visual Design. 11(4) 2017. Indexed in Scorpus, SJR 2017 0.11 2015 – 2016 CS Soo, WS Yap, WM Hon, LY Phang. Mini review: hydrogen and ethanol co-production from waste materials via microbial fermentation. World Journal of Microbiology and Biotechnology 31(10): 1475-1488 (2015) Impact factor: 2.100 Journal Publications (Indexed Journal) L Tawei, ZY Ng, MK Veerapen, RWK Yap, WM Hon, RLH Lim. Association of FTO 17817449 variant with obesity and the energy intake and physical activity parameters in Malaysian adolescents. Malaysian Journal of Biochemistry and Molecular Biology 1:16-23 (2016). Indexed in Scorpus, SJR 2017 0.10 2014 ZY Ng, MK Veerapen, WM Hon, RLH Lim. Association of leptin/receptor and TNF-α gene variants with adolescent obesity in Malaysia. Pediatrics International 56(5): 689–697 (2014) Impact factor: 0.731 Journal Publications (Indexed Journal) Yap RWK, Masaki M, Shidoji Y and Hon WM. Association and interaction effect between VEGFR2 gene polymorphisms and dietary pattern on blood lipids in Malaysian adults. J Nutritional Therapeutics 3:160-167 (2014) Indexed in EBSCO 2012 RWK Yap, Y Shidoji, WM Hon, M Masaki. Interaction between VEGF Receptor-2 Gene Polymorphisms and Dietary Patterns on Blood Glucose and Lipid Levels in Chinese Malaysian Adults. J Nutrigenet Nutrigenomics 2011(4):309-321. (2012) Impact factor: 2.027 RWK Yap, Y Shidoji, WM Hon, M Masaki. Association and interaction between dietary pattern and VEGF receptor-2 (VEGFR2) gene polymorphisms on blood lipids in Chinese Malaysian and Japanese adults. Asia Pac J Clin Nutr 21 (2):302-311. (2012) Impact factor: 1.335 Journal Publications (Indexed Journal) RWK Yap, Y Shidoji, WM Hon, M Masaki. Association and Interaction Effect between VEGF Receptor-2 (VEGFR-2) Gene Polymorphisms and Dietary Pattern on Blood Uric Acid in Malays and Indians. Mal J Nutr 18(3): 307-317. (2012) Indexed in Scorpus, SJR 2017 0.14 JH Foong, WM Hon, CW Ho. Bioactive compounds determination in fermented liquid dragon fruit (Hylocereus Polyrhizus). Borneo Sci 31: 31-48 (2012) Indexed in MyCite 2000 – 2006 WM Hon, S Moochhalla and HE Khoo. Adenosine and its receptor agonists regulate nitric oxide production in Raw 264.7 macrophages via both receptor binding and its downstream metabolites – inosine. Life Sci. 66(19): 1781-1793. (2000) Impact factor: 2.702 WM Hon, EJC Lee and KH Lee. Effect of haemodialysis on plasma nitric oxide levels. Artificial Organs. 24 (5): 387-90. (2000) Impact factor: 2.111 WM Hon, KH Lee and HE Khoo. Nitric oxide in liver diseases – friends, foe or just passerby. Annals of New York Academy of Science. 962: 275-295. (2002) Impact factor: 4.039 CL Wei, WM Hon, KH Lee, M Mori, T Gotoh and HE Khoo. Induction of Arginase II in Livers of Bile Duct-ligated Rats. Biochemical Pharmacology. 63: 1043-1050. (2002) Impact factor: 5.009 CL Wei, WM Hon, KH Lee, WM Hon. Differential expression and regulation of nitric oxide synthases in cirrhotic livers of bile duct-ligated rats. Nitric Oxide. 7(2):91-102. (2002) Impact factor: 3.548 CL Wei, KH Lee, Khoo HE, WM Hon. Expression of heme oxygenase in cirrhotic rat liver. J Pathology. 199: 324-334. (2003) Impact factor: 7.429 CL Wei, WM Hon, KH Lee, Khoo HE. Temporal Expression of Hepatic Inducible Nitric Oxide Synthase in Liver Cirrhosis. World Journal of Gastroenterology. 11(3): 362-367. (2005) Impact factor: 3.365 CL Wei, WM Hon, KH Lee, Khoo HE. Chronic administration of aminoguanidine reduces vascular nitric oxide production and attenuates live damage in bile duct-ligated rats. Liver International. 25: 647-656. (2005) Impact factor: 4.500 BJ Goh, BT Tan, WM Hon, KH Lee, Khoo HE. Nitric oxide synthase and heme oxygenase expression in human cirrhosis. World Journal of Gastroenterology. World Journal of Gastroenterology. 28: 12(4):588-94. (2006) Impact factor: 3.365 1995 – 1998 HE Khoo, WM Hon, SH Lee and R Yuen. Effects of stonustoxin (lethal factor from Synanceja Horrida venom) on platelet aggregation. Toxicon. 33: 1033-1041 (1995). Impact factor: 2.492 WM Hon, HE Khoo, SS Ngoi and SM Moochhala. Effects of adenosine receptor agonists on nitric oxide release in mouse during endotoxaemia. Biochem. Pharmacol. 50: 45-47. (1995). Impact factor: 5.009 TC Lim, SM Moochhala, TL Tan Walter, VJS Chhatwal, S Suhumaran, WM Hon and HE Khoo. Down regulation of inducible nitric oxide synthase expression in keloids. Plastic and Reconstructive Surgery. 98: 911-912. (1996) Impact factor: 2.993 SM Moochhala, WM Hon, VSJ Chhatwal and HE Khoo. Lipopolysaccharide-induced inducible nitric oxide synthase expression in mice: Pharmacological evaluation of adenosine agonists. Eur. J. Pharmacol. 316: 287-296. (1996) Impact factor: 2.896 WM Hon, VSJ Chhatwal, HE Khoo and SM Moochhala. Histochemical method for detection of nitric oxide synthase activity in cell cultures. Biotechnic & Histochemistry. 72: 29-32. (1997) Impact factor: 1.444 WM Hon, SM Moochhala and HE Khoo. Adenosine and its receptor agonists potentiate nitric oxide synthase expression induced by lipopolysaccharide in RAW 264.7 murine macrophages. Life Sci. 60: 1327-1335. (1997) Impact factor: 2.702 Journal Publications (Indexed Journal) WM Hon, HE Khoo and SM Moochhalla. Nitric oxide in Septic Shock: Directions for Future Therapy? Ann Acad Med Singapore. 27: 414-421. (1998) Indexed in Scorpus, SJR 2017 0.25 Special Article WM Hon. From Doing Science to Servicing Science. Science Magazine. Apr 25, 2003 研究资助 / 顾问项目 研究资助 题目: 制定马来西亚零售店预包装食品营养标签设计指南 期限: 2015 – 2018年 赞助/资助: 马来西亚高等教育部FRGS资助计划(马币10万令吉) 题目: 成孔毒素与人类细胞膜特异性结合的研究 (Investigation of the specific binding of pore-forming toxin to human cell membrane) 期限: 2013 – 2017 年 赞助/资助: 马来西亚高等教育部FRGS资助计划(马币10万令吉) 题目: Enhanced Biohydrogen by Genetic Modification 期限: 2012-2015 Sponsor/Grant: FRGS grant scheme of Ministry of Higher Education, Malaysia (RM212,500) 题目: Hydrogen Production by Recombinant Ethanol-Producing Bacteria 期限: 2012-2014 Sponsor/Grant: Malaysia Toray Science Foundation(RM25,000) 题目: Investigation and Optimization of the Nutrient Flux in Seawater Closed-recirculating Integrated System for the Culture of Fish and Seaweed 期限: 2010-2014 Sponsor/Grant: UCSI University Research Grant Scheme (RM350,000) 题目: Lipid, cholesterol and triacylglycerol lowering ability of an agribiotechnology health based product 期限: 2011-2015 Sponsor/Grant: FRGS grant scheme of Ministry of Higher Education, Malaysia (RM65,000) 题目: Screening and functional analysis of cosmeceutical peptides from palm kernel cake extracts 期限: 2010-2014 Sponsor/Grant: UCSI University Research Grant Scheme (RM150,000) 题目: Genotyping of candidate genes related to myopia and obesity in a cohort of secondary school students (Top up) 期限: 2010-2012 Sponsor/Grant: UCSI University Research Grant Scheme (RM55,000) 题目: Genotyping of candidate genes related to myopia and obesity in a cohort of secondary school students 期限: 2010-2014 Sponsor/Grant: FRGS grant scheme of Ministry of Higher Education, Malaysia (RM38,640) 题目: Development of Diagnostic Kits for Pathogens, Diagnostic Chip for Liver Disease, Bio-informatics data sets for mouse for liver disease, Micro PCR Field Application, Real-time PCR machine for fieldPrototype DNA synthesiser 期限: 2002-2005 Sponsor/Grant: Research Incentive scheme for companies (RISC) by Economic Development Board, Singapore (Awarded S$1.3 million) 题目: Expression of Gastrin-releasing peptide receptor in lung cancer 期限: 2000-2003 Sponsor/Grant: Singapore Cancer Society (S$21,500) 题目: The role of vitamin E coated membranes in haemodialysis induced inflammatory changes and oxidative stresses (NMRC/0291/1998) 期限: 1998-2001 Sponsor/Grant: National Medical Research Council, Singapore (S$156,500) 题目: The role of nitric oxide in liver disease (NMRC/0254/1997) 期限: 1997-2001 Sponsor/Grant: National Medical Research Council, Singapore (S$164,000) 咨询工作 2018 – 2020 年 Vice-Chair of the Curriculum Committee of United Chinese School Committee’s Association of Malaysia (UCSCAM) oversea the Overall Curriculum of Chinese Independent School Council member of the Working Committee of United Chinese School Committee’s Association of Malaysia (UCSCAM) oversea the strategic direction of Chinese Independent School in Malaysia 2008 – Present Subject advisor for Biology in the Curriculum Department for United Chinese School Committee’s Association of Malaysia (UCSCAM) 2016 – 2018 Council member of the Curriculum Committee of United Chinese School Committee’s Association of Malaysia (UCSCAM) oversea the Overall Curriculum of Chinese Independent School 2016 – 2017 Working members for the Science Outlook 2017 – Converging towards progressive Malaysia by Academic of Science Malaysia 2011 Auditor for MyQuest, Ministry of Higher Education 2010 Internal Judge for the UCSIU Bizplan Competition, Malaysia 2009 – 2010 External inspector of Diploma in Education for New Era College 2007 – 2009 Panelist for LAN Biotechnology standard and criteria committee 监督 博士论文: NO在肝硬化中的作用(1998-2002年) Wei Changli博士(与生物化学Khoo HE 副教授及新加坡国立大学医学Lee KH副教授共同督导) 博士论文: NO在肝癌中的作用(2002-2010年) Goh Beatrice博士(与新加坡国立大学生物化学Khoo HE副教授共同督导) 硕士论文: 从农业废弃物中筛选具有美容品性质的化合物(2010-2012年) Rachael Choi Wai Chuen女士 硕士论文: 木瓜蛋白酶和菠萝蛋白酶cDNA编码序列分析及重组木瓜蛋白酶和菠萝蛋白酶的适销性(2010-2012年) Hishmath Ibrahim 女士 硕士论文: 重组木瓜蛋白酶的分离、复制与表达(2011-2013年) Nur Wahida Hamdan 女士 硕士论文: 马来西亚青少年中LAMA1和Pax6基因多态性与近视相关性研究(2011-2013年) Lana Zuhair 女士 博士论文: 通过基因改造和生物发酵调控氢和乙醇的生产(2013-2017年) Soo Chiu Shyan博士(与马来西亚博特拉大学Phang LY副教授共同督导) 硕士论文: 营养追踪移动应用:马来西亚年轻人用户体验分析(2017-持续进行) Kwang Yong Tik先生(与马来西亚伍伦贡伯乐学府Pouline Koh博士共同督导) 奖项和荣誉 奖励和敬意 2002年11月受邀在新加坡举行的第九届东盟医学实验室技术会议上,以“基于PCR的病原体分子诊断”为题发表演说 受邀为提交国际同行评审期刊的论文担任审稿人——《一氧化氮》 (2003年) 获邀在马来西亚医学研究所举办“PCR及实时PCR”工作坊 (2004年10月25及26日) 思特雅大学(UCSI)卓越研究中心研究委员会特邀成员(2006-2007年) 科学与艺术进步杂志(JASA)编辑委员会成员(2007-2009年) 第20届大学间生物化学研讨会评审团,2009年3月马来西亚博特拉大学(UPM)举行 2010年日本长崎大学“预防慢性疾病的分子生物学”研讨会特邀演讲者 2011年6月22日吉隆坡绿色商业论坛“为国家供电:绿色是前进的道路”特邀演讲者 2012年7月18日至19日(吉隆坡),应邀在马来西亚医学委员会第37届年会发表“马来西亚人多因素疾病的遗传研究”演说 。 2013年思特雅大學(UCSI)高影响力研究奖补助金奖类别中,获得总值马币6万5千令吉的外部研究经费。 2013年思特雅大學(UCSI)高影响力研究奖补助金奖类别中,获得总值马币21万2千5百令吉的外部研究经费。 参与专业协会和委员会 新加坡生物化学和分子生物学学会(SSBMB)助理秘书长(1996年) SSBMB秘书长(1997-1999年) SSBMB财务总监(2000-2002年) SSBMB秘书长(2002-2004年) SSBMB理事会成员(2004-2006年) SSBMB会员(2007年至今) 新加坡国家科学院(SNAS)理事会成员(1997-1999年) SNAS财务总监,2000-2002年 思特雅大學(UCSI)应用科学学院学生协会(SASAS)顾问(2006 – 2010年) 马来西亚生物化学和分子生物学学会会员(2012年至今) 思特雅大學(UCSI)教学委会教育委员副主席(2007-2013年) 思特雅大學(UCSI)教育委会成员(2009-2013年) 思特雅大學(UCSI)考试委会成员(2009-2013年) 思特雅大學(UCSI)质量保证与加强教育委会成员(2009-2013年) 考试委员会主席,伍伦贡(马)伯乐大学学院及学院(2013年至今) 教学委员会教育委员主席,伍伦贡(马)伯乐大学学院及学院(2013年至今) 研究与学术研究教育委员主席,伍伦贡(马)伯乐大学学院(2013年至今) 奖学金与奖励委员会主席,伍伦贡(马)伯乐大学学院及学院(2013-2015年) 奖学金及奖项委员会成员,伍伦贡(马)伯乐大学学院及学院(2015年至今) 教育委员与管理委员会成员,伍伦贡(马)伯乐大学学院和学院(2013年至今)